Conor McGregor has talked about making history.

Now, he has the chance.

McGregor, the reigning UFC featherweight champion, challenges Eddie Alvarez in the main event of UFC 205. The bout was confirmed by UFC president Dana White late Monday night on ESPN.

Set for November 12, the card takes place from Madison Square Garden and marks the first UFC event since New York legalized MMA. Along with Alvarez-McGregor, Tyron Woodley defends his welterweight title vs. Stephen Thompson and Karolina Kowalkiewicz challenges Joanna Jedrzejczyk for the strawweight belt.

McGregor would become just the third UFC fighter in history to be a multi-division champion, but the first to hold two titles at once. BJ Penn and Randy Couture are the others, and Penn had a chance to win the welterweight belt while holding the lightweight title, but fell to Georges St-Pierre.

Alvarez, the first fighter to be a champion in both the UFC and Bellator, won the belt earlier this year when he finished Rafael dos Anjos. He immediately called for a matchup with McGregor, who has not fought at lightweight since competing in Cage Warriors.

Below is the current fight card:

UFC Lightweight Championship
Eddie Alvarez (c) vs. Conor McGregor

UFC Welterweight Championship
Tyron Woodley (c) vs. Stephen Thompson

UFC Straweight Championship
Joanna Jedrzejczyk vs. Karolina Kowalkiewicz

Middleweight: Chris Weidman vs. Yoel Romero

Welterweight: Donald Cerrone vs. Kelvin Gastelum

Female Bantamweight: Miesha Tate vs. Raquel Pennington

Middleweight: Chris Weidman vs. Yoel Romero

Middleweight: Tim Kennedy vs. Rashad Evans

Lightweight: Thiago Alves vs. Jim Miller

Middleweight: Tim Boetsch vs. Rafael Natal

Female Bantamweight: Liz Carmouche vs. Katlyn Chookagian

Welterweight: Lyman Good vs. Belal Muhammad