Fans in Toronto are likely destined to be treated to a title-fight when the UFC rolls through town on September 22 for UFC 152. According to UFC President Dana White, the organization is targeting the event for Junior dos Santos’ second championship defense where he’ll face former heavyweight king Cain Velasquez in headlining action.

White informed media of his plans after the post-event presser for UFC on FX 3. The show is already set to feature iconic veteran B.J. Penn’s return to the Octagon where he’ll face 22-year old Canadian prodigy Rory MacDonald.

The fight between Dos Santos-Velasquez marks a role reversal of their meeting in November where “Cigano” entered as contender and Velasquez as champion. Whether the result will be the same with Dos Santos exiting with the belt or follow previous form and see the challenger win via knockout remains to be seen.

Dos Santos holds an overall record of 15-1 with ten consecutive victories including nine inside the Octagon. During the run he’s dished out strike-based finishes of Velasquez, Stefan Struve, Mirko Filipovic, Gabriel Gonzaga, and most recently Frank Mir.

By comparison, Velasquez is 10-1 with a TKO win over Antonio Silva in his only fight since falling to Dos Santos on FOX. He has had similar success when it comes to stopping opponents with nine to his credit such as those against Antonio Rodrigo Nogueira and Brock Lesnar.